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| DV AND MDV DATA ITEMS |
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MEANING: Dependent Variable (DV) and Missing Dependent Variable (DV) data items
for NONMEM
CONTEXT: $INPUT record and NONMEM data set
USAGE:
$INPUT ... DV MDV ...
DISCUSSION:
DV and MDV label NONMEM's dependent variable (DV) and missing depen-
dent variable (MDV) data items, respectively.
The dependent variable (DV) data item is required by NONMEM. It is
the observed value associated with the data record.
The missing dependent variable (MDV) data item is optional. If it is
present, then the ID data item must also be present.
Values of MDV are:
0 The DV data item is an observed value, i.e., DV is not miss-
ing.
1 The DV data item is not regarded an observed value, i.e., DV
is missing. The DV data item is ignored. |
100 Same as MDV=0, but this record is ignored during Estimation |
and Covariance Steps. During other steps, MDV will changed |
to 0. |
101 Same as MDV=1, but this record is ignored during Estimation |
and Covariance Steps. During other steps, MDV will changed |
to 1. |
Reserved variables MDVI1, MDVI2, MDVI3 can be used to over- |
ride values of MDV>100. These variables are defined in |
include file nonmem_reserved_general, which needs to be |
copied from util to the present run directory so NMTRAN has |
access to it.
With PREDPP, event records whose types are dose, other-type, reset, or
reset-dose (i.e., which have EVID values 1, 2, 3, 4) must all have
MDV=1. NM-TRAN will append the MDV data item if PREDPP is used and
MDV is not present on the $INPUT record.
(See observation records).
REFERENCES: Guide I Section B.1, C.4.3
REFERENCES: Guide VI Section II, V.A
REFERENCES: Guide IV Section III.B.2, V.B
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