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| DATA_AVERAGE EXAMPLE |
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A template record is a data record that contains a non-zero value for
the raw-data (RAW_) data item. Only the DV values with those observa-
tion records (i.e., records with MDV=0) matching the template data
record will be included in the average. This average replaces the DV
item in the template record, and it may be displayed in a table or
scatterplot.
An observation record matches a template if all its data items are
identical to all those on the template, except that the values of NON-
MEM data items do not affect the match. (Any nonNONMEM data item type
may in fact be excluded from the match (See omit)).
Example 1
Here is a fragment of a data set (which may or may not actually be for
PREDPP):
#ID TIME AMT WT AGE EVID MDV DV RAW_ GEND
1 5 0 70 50 0 1 2 1 1 template record
4 5 0 70 50 0 0 4 0 1 observation record
These two records match. The NONMEM items are the ID, MDV, DV, and
RAW_ items. The DV item with the observation record will be included
in the average. The DV item in the template record is ignored for the
purpose of computing the average (MDV=1); the displayed DV item with
this record will be the average value, and the displayed RES item will
be the difference between this average and the PRED item. The average
is taken over all records matching the TIME, AMT, WT, AGE, EVID, and
GEND items of the template record.
If the omit record
$OMIT GEND
appears, then the two records
#ID TIME AMT WT AGE EVID MDV DV RAW_ GEND
1 5 0 70 50 0 1 2 1 1 template record
4 5 0 70 50 0 0 4 0 2 observation record
also match. In this case the average is taken over all records match-
ing the TIME, AMT, WT, AGE, and EVID items of the template record.
Example 2
Here is an example of categorical dose-response with four different
bolus doses per individual (separated by washouts), and data averages
are formed for each of the four doses.
#ID DOSE DV MDV RAW_
100 5 . 1 1 set DV item to avr. for DOSE=5
100 10 . 1 1 set DV item to avr. for DOSE=10
100 20 . 1 1 set DV item to avr. for DOSE=20
100 40 . 1 1 set DV item to avr. for DOSE=40
1 5 1 0 0
1 10 1 0 0
1 20 2 0 0
1 40 2 0 0
2 5 1 0 0
2 10 1 0 0
2 20 1 0 0
2 40 1 0 0
3 5 1 0 0
3 10 2 0 0
3 20 2 0 0
3 40 3 0 0
.
.
Example 3
An average of a PRED-defined item may also be displayed.
$ABBREV COMRES=1 COMSAV=1
...
$PRED
COM(1)=LOG(DV)
...
$TABLE COM(1)=LDV
For template records, the value of LDV displayed in the table is the
average of LOG DV over all observation records matching the template.
(See data average block, raw).
REFERENCES: none.
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Created by nmhelp2html v. 1.0 written by Niclas Jonsson (Modified by AJB 5/2006,11/2007,10/2012)